Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1360793Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 1360794Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 1361005Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 1361051Protein NAD-dependent deacetylase sirtuin-5 [142128] (1 species)
  7. 1361052Species Human (Homo sapiens) [TaxId:9606] [142129] (2 PDB entries)
    Uniprot Q9NXA8 36-302

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 2b4y:
    1. 1361053Domain d2b4ya1: 2b4y A:36-302 [127868]
      complexed with apr, epe, zn
    2. 1361054Domain d2b4yb_: 2b4y B: [127869]
      automated match to d2b4ya1
      complexed with apr, epe, zn
    3. 1361055Domain d2b4yc_: 2b4y C: [127870]
      automated match to d2b4ya1
      complexed with apr, epe, zn
    4. 1361056Domain d2b4yd_: 2b4y D: [127871]
      automated match to d2b4ya1
      complexed with apr, epe, zn
  2. Domain(s) for 2nyr:
    1. 1361057Domain d2nyra_: 2nyr A: [138827]
      automated match to d2b4ya1
      complexed with svr, zn
    2. 1361058Domain d2nyrb_: 2nyr B: [138828]
      automated match to d2b4ya1
      complexed with svr, zn

More info for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 NAD-dependent deacetylase sirtuin-5

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 NAD-dependent deacetylase sirtuin-5: