Lineage for Protein: NAD-dependent deacetylase NpdA
- Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds) 
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-likeSuperfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) 
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domainProtein NAD-dependent deacetylase NpdA [142126] (1 species)
Species:
Thermotoga maritima [TaxId:2336] [142127] (7 PDB entries)
Uniprot Q9WYW0 1-245- Domain for 1yc5:
Domain d1yc5a1: 1yc5 A:1-245 [122910]
complexed with nca, zn
- Domain for 2h4h:
Domain d2h4ha_: 2h4h A: [164944]
automated match to d1yc5a1
complexed with nad, zn; mutant
- Domains for 2h59:
Domain d2h59a_: 2h59 A: [164949]
automated match to d1yc5a1
complexed with 3od, apr, zn
Domain d2h59b_: 2h59 B: [164950]
automated match to d1yc5a1
complexed with 3od, apr, zn
- Domain for 3d4b:
Domain d3d4ba_: 3d4b A: [157291]
automated match to d1yc5a1
complexed with dzd, zn
- Domain for 3d81:
Domain d3d81a_: 3d81 A: [157437]
automated match to d1yc5a1
complexed with zn
- Domain for 3jr3:
Domain d3jr3a_: 3jr3 A: [178717]
automated match to d1yc5a1
complexed with zn
- Domain for 3pdh:
Domain d3pdha_: 3pdh A: [183672]
automated match to d1yc5a1
complexed with zn
- Domain for 1yc5:
More info for Protein NAD-dependent deacetylase NpdA from c.31.1.5: Sir2 family of transcriptional regulators
Timeline for Protein NAD-dependent deacetylase NpdA from c.31.1.5: Sir2 family of transcriptional regulators:
- Protein NAD-dependent deacetylase NpdA from c.31.1.5: Sir2 family of transcriptional regulators first appeared in SCOP 1.73
- Protein NAD-dependent deacetylase NpdA from c.31.1.5: Sir2 family of transcriptional regulators appears in SCOPe 2.07