SCOPe 2.08: Protein: Retinal dehydrogenase/reductase 3

Lineage for Protein: Retinal dehydrogenase/reductase 3

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
has additional subdomain(s) that are not in the common domain

Protein Retinal dehydrogenase/reductase 3 [141907] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [141908] (15 PDB entries)
Uniprot Q9BPX1 4-253
1. Domain for 1yde:
  - Domain d1ydea1: 1yde A:4-253 [122980]
    Other proteins in same PDB: d1ydeb_, d1ydec_, d1yded_, d1ydee_, d1ydef_, d1ydeg_, d1ydeh_, d1ydei_, d1ydej_, d1ydek_, d1ydel_, d1ydem_, d1yden_, d1ydeo_, d1ydep_
2. Domain for 5en4:
  - Domain d5en4a_: 5en4 A: [326411]
    automated match to d1ydef_
    complexed with 5q6, na, nad
3. Domain for 5hs6:
  - Domain d5hs6a1: 5hs6 A:4-257 [319512]
    Other proteins in same PDB: d5hs6a2
    automated match to d1ydef_
    complexed with j3z, na, nad
4. Domain for 5icm:
  - Domain d5icma1: 5icm A:5-256 [319504]
    Other proteins in same PDB: d5icma2
    automated match to d1ydef_
    complexed with f45, glc, na, nad
5. Domains for 5ics:
  1. Domain d5icsa_: 5ics A: [319564]
    Other proteins in same PDB: d5icsc2
    automated match to d1ydef_
  2. Domain d5icsc1: 5ics C:4-259 [319624]
    Other proteins in same PDB: d5icsc2
    automated match to d1ydef_
  3. Domain d5icsd1: 5ics D:4-259 [319579]
    Other proteins in same PDB: d5icsc2
    automated match to d1ydef_
  4. Domain d5icsf_: 5ics F: [319604]
    Other proteins in same PDB: d5icsc2
    automated match to d1ydef_
6. Domain for 5js6:
  - Domain d5js6a1: 5js6 A:4-270 [319636]
    Other proteins in same PDB: d5js6a2
    automated match to d1ydef_
    complexed with cl, nad, pg4, pge
7. Domain for 5jsf:
  - Domain d5jsfa1: 5jsf A:4-270 [319643]
    Other proteins in same PDB: d5jsfa2
    automated match to d1ydef_
    complexed with cl, na, nad, pge
8. Domain for 5l7t:
  - Domain d5l7ta1: 5l7t A:4-256 [327438]
    Other proteins in same PDB: d5l7ta2
    automated match to d1ydef_
    complexed with 6qj, na, nad
9. Domain for 5l7w:
  - Domain d5l7wa1: 5l7w A:4-254 [327430]
    Other proteins in same PDB: d5l7wa2
    automated match to d1ydef_
    complexed with 6qu, bgc, na, nad
10. Domain for 5l7y:
  - Domain d5l7ya1: 5l7y A:4-256 [327432]
    Other proteins in same PDB: d5l7ya2
    automated match to d1ydef_
    complexed with 6qo, na, nad
11. Domain for 6emm:
  - Domain d6emma1: 6emm A:4-270 [359549]
    Other proteins in same PDB: d6emma2
    automated match to d5icsa_
    complexed with nad, peg, pg4, sal
12. Domain for 6gbt:
  - Domain d6gbta_: 6gbt A: [368070]
    automated match to d5icsa_
    complexed with dms, f45, na, nad; mutant
13. Domain for 6gtu:
  - Domain d6gtua1: 6gtu A:4-270 [370013]
    Other proteins in same PDB: d6gtua2
    automated match to d5icsa_
    complexed with 45n, cl, nad, pge
14. Domain for 6zde:
  - Domain d6zdea_: 6zde A: [401537]
    automated match to d1ydea1
    complexed with na, nad, qfz
15. Domain for 6zdi:
  - Domain d6zdia_: 6zdi A: [401555]
    automated match to d1ydea1
    complexed with na, nad, qft

More info for Protein Retinal dehydrogenase/reductase 3 from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Retinal dehydrogenase/reductase 3 from c.2.1.2: Tyrosine-dependent oxidoreductases:

Protein Retinal dehydrogenase/reductase 3 from c.2.1.2: Tyrosine-dependent oxidoreductases first appeared in SCOP 1.73
Protein Retinal dehydrogenase/reductase 3 from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOPe 2.07