Lineage for Protein: Peroxisomal multifunctional enzyme type 2

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
    has additional subdomain(s) that are not in the common domain
  6. 2842658Protein Peroxisomal multifunctional enzyme type 2 [141900] (1 species)
    17-beta-hydroxysteroid dehydrogenase 4

Species:

  • 2842659Human (Homo sapiens) [TaxId:9606] [141901] (1 PDB entry)
    Uniprot P51659 2-303
    the structure of C-terminal domain is also known, PDB entry 1S9C
    • Domains for 1zbq:
      1. 2842660Domain d1zbqa1: 1zbq A:3-304 [124862]
        complexed with nad
        has additional insertions and/or extensions that are not grouped together
      2. 2842661Domain d1zbqb_: 1zbq B: [124863]
        automated match to d1zbqa1
        complexed with nad
        has additional insertions and/or extensions that are not grouped together
      3. 2842662Domain d1zbqc_: 1zbq C: [124864]
        automated match to d1zbqa1
        complexed with nad
        has additional insertions and/or extensions that are not grouped together
      4. 2842663Domain d1zbqd_: 1zbq D: [124865]
        automated match to d1zbqa1
        complexed with nad
        has additional insertions and/or extensions that are not grouped together
      5. 2842664Domain d1zbqe_: 1zbq E: [124866]
        automated match to d1zbqa1
        complexed with nad
        has additional insertions and/or extensions that are not grouped together
      6. 2842665Domain d1zbqf_: 1zbq F: [124867]
        automated match to d1zbqa1
        complexed with nad
        has additional insertions and/or extensions that are not grouped together

More info for Protein Peroxisomal multifunctional enzyme type 2 from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Peroxisomal multifunctional enzyme type 2 from c.2.1.2: Tyrosine-dependent oxidoreductases:

  • Protein Peroxisomal multifunctional enzyme type 2 from c.2.1.2: Tyrosine-dependent oxidoreductases first appeared in SCOP 1.73
  • Protein Peroxisomal multifunctional enzyme type 2 from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOPe 2.07