Lineage for Species: Thermus thermophilus [TaxId: 274]

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families) Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (13 proteins) the catalytic lysine forms schiff-base intermediate with substrate possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein Decameric fructose-6-phosphate aldolase/transaldolase [75085] (3 species) forms helix-swapped pentamers

7. Species Thermus thermophilus [TaxId:274] [141836] (1 PDB entry) Uniprot Q5SJE8 1-211 clear orthologue of the E.coli protein; annotated as transaldolase in UniProt