Class a: All alpha proteins [46456] (286 folds) |
Fold a.60: SAM domain-like [47768] (16 superfamilies) 4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins |
Superfamily a.60.2: RuvA domain 2-like [47781] (7 families) duplication: contains two helix-hairpin-helix (HhH) motifs |
Family a.60.2.5: Hef domain-like [140629] (4 proteins) helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft) |
Protein DNA excision repair protein ERCC-1 [140630] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [140631] (3 PDB entries) Uniprot P07992 219-296! Uniprot P07992 220-297 |
Domain d1z00a1: 1z00 A:220-297 [124294] Other proteins in same PDB: d1z00b1 |
Domain d2a1jb1: 2a1j B:219-296 [126001] Other proteins in same PDB: d2a1ja1 protein/DNA complex; complexed with hg |
Domain d2muta_: 2mut A: [274219] Other proteins in same PDB: d2mutb_ automated match to d1z00a1 mutant |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.60.2.5 DNA excision repair protein ERCC-1: