Lineage for Species: Mycobacterium tuberculosis [TaxId: 1773]

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.25: Ferritin-like [47239] (4 superfamilies) core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection

4. Superfamily a.25.3: EsxAB dimer-like [140453] (1 family) (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals

5. Family a.25.3.1: ESAT-6 like [140454] (2 proteins) Pfam PF06013; the conserwed WxG motif makes the turn at the alpha-hairpin tip

6. Protein ESAT-6, EsxA [140457] (1 species) 6 kDa early secretory antigenic target

7. Species Mycobacterium tuberculosis [TaxId:1773] [140458] (1 PDB entry)