SCOPe 2.01: Family a.25.3.1: ESAT-6 like

Lineage for Family a.25.3.1: ESAT-6 like

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.25: Ferritin-like [47239] (6 superfamilies)
   core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection

4. Superfamily a.25.3: EsxAB dimer-like [140453] (1 family)
   (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals

5. Family a.25.3.1: ESAT-6 like [140454] (3 proteins)
   Pfam PF06013; the conserwed WxG motif makes the turn at the alpha-hairpin tip

Proteins:

1. ESAT-6 like protein EsxB [140455] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [140456] (1 PDB entry)
     Uniprot P0A566 1-99

2. ESAT-6, EsxA [140457] (1 species)
   6 kDa early secretory antigenic target

   • Species Mycobacterium tuberculosis [TaxId:1773] [140458] (2 PDB entries)
     Uniprot P0A564 1-94

3. automated matches [191103] (1 species)
   not a true protein

   • Species Mycobacterium tuberculosis [TaxId:83332] [189126] (1 PDB entry)

More info for Family a.25.3.1: ESAT-6 like

Timeline for Family a.25.3.1: ESAT-6 like:

• Family a.25.3.1: ESAT-6 like first appeared in SCOP 1.73
  
• Family a.25.3.1: ESAT-6 like appears in SCOP 1.75
  
• Family a.25.3.1: ESAT-6 like appears in SCOPe 2.02
  
• Family a.25.3.1: ESAT-6 like appears in the current release, SCOPe 2.08