Lineage for Family a.25.3.1: ESAT-6 like

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1988413Fold a.25: Ferritin-like [47239] (6 superfamilies)
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
  4. 1991323Superfamily a.25.3: EsxAB dimer-like [140453] (2 families) (S)
    (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals
  5. 1991324Family a.25.3.1: ESAT-6 like [140454] (3 protein domains)
    Pfam PF06013; the conserwed WxG motif makes the turn at the alpha-hairpin tip

Protein Domains:

  1. 1991325ESAT-6 like protein EsxB [140455] (1 species)
  2. 1991328ESAT-6, EsxA [140457] (1 species)
    6 kDa early secretory antigenic target
  3. 1991333automated matches [191103] (1 species)
    not a true protein

More info for Family a.25.3.1: ESAT-6 like

Timeline for Family a.25.3.1: ESAT-6 like: