SCOPe 2.08: Protein: Lysine-specific histone demethylase 1, LSD1

Lineage for Protein: Lysine-specific histone demethylase 1, LSD1

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
Superfamily a.4.1: Homeodomain-like [46689] (21 families)
consists only of helices
Family a.4.1.18: SWIRM domain [140222] (4 proteins)
Pfam PF04433; contains extra N-terminal helix
Protein Lysine-specific histone demethylase 1, LSD1 [140227] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [140228] (28 PDB entries)
Uniprot O60341 169-279
1. Domain for 2com:
  - Domain d2coma1: 2com A:8-118 [130679]
    Other proteins in same PDB: d2coma2, d2coma3
2. Domain for 2dw4:
  - Domain d2dw4a1: 2dw4 A:172-273 [146594]
    Other proteins in same PDB: d2dw4a2, d2dw4a3
    automatically matched to 2IW5 A:171-273
    complexed with fad
3. Domain for 2ejr:
  - Domain d2ejra1: 2ejr A:172-273 [146877]
    Other proteins in same PDB: d2ejra2, d2ejra3
    automatically matched to 2IW5 A:171-273
    complexed with f2n
4. Domain for 2h94:
  - Domain d2h94a1: 2h94 A:172-273 [147245]
    Other proteins in same PDB: d2h94a2, d2h94a3
    automatically matched to 2IW5 A:171-273
    complexed with fad, hg
5. Domain for 2iw5:
  - Domain d2iw5a1: 2iw5 A:171-273 [145539]
    Other proteins in same PDB: d2iw5a2, d2iw5a3, d2iw5b1, d2iw5b2
    complexed with cl, fad, gol, nh4
6. Domain for 2uxn:
  - Domain d2uxna1: 2uxn A:173-273 [145760]
    Other proteins in same PDB: d2uxna2, d2uxna3, d2uxnb1
    automatically matched to 2IW5 A:171-273
    complexed with cl, fda, gol
7. Domain for 2uxx:
  - Domain d2uxxa1: 2uxx A:171-273 [152310]
    Other proteins in same PDB: d2uxxa2, d2uxxa3, d2uxxb1, d2uxxb2
    automated match to d2iw5a1
    complexed with cl, faj, gol
8. Domain for 2xaf:
  - Domain d2xafa1: 2xaf A:171-273 [264562]
    Other proteins in same PDB: d2xafa2, d2xafa3, d2xafb1, d2xafb2
    complexed with fad, tcf
9. Domain for 2xag:
  - Domain d2xaga1: 2xag A:171-273 [264567]
    Other proteins in same PDB: d2xaga2, d2xaga3, d2xagb1, d2xagb2
    complexed with fad, tcf
10. Domain for 2xah:
  - Domain d2xaha1: 2xah A:171-273 [264572]
    Other proteins in same PDB: d2xaha2, d2xaha3, d2xahb1, d2xahb2
    complexed with 3pl, fad
11. Domain for 2xaj:
  - Domain d2xaja1: 2xaj A:171-273 [264577]
    Other proteins in same PDB: d2xaja2, d2xaja3, d2xajb1, d2xajb2
    complexed with fad, tca
12. Domain for 2xaq:
  - Domain d2xaqa1: 2xaq A:171-273 [264582]
    Other proteins in same PDB: d2xaqa2, d2xaqa3, d2xaqb1, d2xaqb2
    complexed with fad, m84
13. Domain for 2xas:
  - Domain d2xasa1: 2xas A:171-273 [264587]
    Other proteins in same PDB: d2xasa2, d2xasa3, d2xasb1, d2xasb2
    complexed with fad, m80
14. Domain for 2z3y:
  - Domain d2z3ya1: 2z3y A:172-273 [154024]
    Other proteins in same PDB: d2z3ya2, d2z3ya3
    automatically matched to 2IW5 A:171-273
    complexed with f2n
15. Domain for 2z5u:
  - Domain d2z5ua1: 2z5u A:172-273 [154167]
    Other proteins in same PDB: d2z5ua2, d2z5ua3
    automatically matched to 2IW5 A:171-273
    complexed with faj
16. Domain for 3zms:
  - Domain d3zmsa1: 3zms A:172-273 [265819]
    Other proteins in same PDB: d3zmsa2, d3zmsa3, d3zmsb1, d3zmsb2
    complexed with fad
17. Domain for 3zmt:
  - Domain d3zmta1: 3zmt A:172-273 [265824]
    Other proteins in same PDB: d3zmta2, d3zmta3, d3zmtb1, d3zmtb2
    complexed with fad
18. Domain for 3zmu:
  - Domain d3zmua1: 3zmu A:172-273 [265829]
    Other proteins in same PDB: d3zmua2, d3zmua3, d3zmub1, d3zmub2
    complexed with fad
19. Domain for 3zmv:
  - Domain d3zmva1: 3zmv A:172-273 [265834]
    Other proteins in same PDB: d3zmva2, d3zmva3, d3zmvb1, d3zmvb2
    complexed with fad
20. Domain for 3zmz:
  - Domain d3zmza1: 3zmz A:172-273 [265839]
    Other proteins in same PDB: d3zmza2, d3zmza3, d3zmzb1, d3zmzb2
    complexed with fad
21. Domain for 3zn0:
  - Domain d3zn0a1: 3zn0 A:171-273 [265844]
    Other proteins in same PDB: d3zn0a2, d3zn0a3, d3zn0b1, d3zn0b2
    complexed with fad
22. Domain for 3zn1:
  - Domain d3zn1a1: 3zn1 A:171-273 [265849]
    Other proteins in same PDB: d3zn1a2, d3zn1a3, d3zn1b1, d3zn1b2
    complexed with fad
23. Domain for 4uv8:
  - Domain d4uv8a1: 4uv8 A:171-273 [267479]
    Other proteins in same PDB: d4uv8a2, d4uv8a3, d4uv8b1, d4uv8b2
    complexed with d69
24. Domain for 4uv9:
  - Domain d4uv9a1: 4uv9 A:171-273 [267484]
    Other proteins in same PDB: d4uv9a2, d4uv9a3, d4uv9b1, d4uv9b2
    complexed with d70
25. Domain for 4uva:
  - Domain d4uvaa1: 4uva A:171-273 [267489]
    Other proteins in same PDB: d4uvaa2, d4uvaa3, d4uvab1, d4uvab2
    complexed with d73
26. Domain for 4uvb:
  - Domain d4uvba1: 4uvb A:171-273 [267494]
    Other proteins in same PDB: d4uvba2, d4uvba3, d4uvbb1, d4uvbb2
    complexed with d51
27. Domain for 4uvc:
  - Domain d4uvca1: 4uvc A:171-273 [267499]
    Other proteins in same PDB: d4uvca2, d4uvca3, d4uvcb1, d4uvcb2
    complexed with d52
28. Domain for 4uxn:
  - Domain d4uxna1: 4uxn A:171-273 [269430]
    Other proteins in same PDB: d4uxna2, d4uxna3, d4uxnb1, d4uxnb2
    automated match to d2xafa1
    complexed with fad, m8a

More info for Protein Lysine-specific histone demethylase 1, LSD1 from a.4.1.18: SWIRM domain

Timeline for Protein Lysine-specific histone demethylase 1, LSD1 from a.4.1.18: SWIRM domain:

Protein Lysine-specific histone demethylase 1, LSD1 from a.4.1.18: SWIRM domain first appeared in SCOP 1.73
Protein Lysine-specific histone demethylase 1, LSD1 from a.4.1.18: SWIRM domain appears in SCOPe 2.07