SCOPe 2.06: Family a.4.1.18: SWIRM domain

Lineage for Family a.4.1.18: SWIRM domain

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.1: Homeodomain-like [46689] (20 families)
   consists only of helices

5. Family a.4.1.18: SWIRM domain [140222] (4 proteins)
   Pfam PF04433; contains extra N-terminal helix

Proteins:

1. Lysine-specific histone demethylase 1, LSD1 [140227] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [140228] (28 PDB entries)
     Uniprot O60341 169-279

2. Transcription regulatory protein swi3 [140223] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [140224] (1 PDB entry)
     Uniprot P32591 311-395

3. Transcriptional adaptor 2-like, TADA2L [140225] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [140226] (3 PDB entries)
     Uniprot Q8CHV6 343-443! Uniprot Q8CHV6 355-443

4. automated matches [254593] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [255400] (1 PDB entry)

More info for Family a.4.1.18: SWIRM domain

Timeline for Family a.4.1.18: SWIRM domain:

• Family a.4.1.18: SWIRM domain first appeared in SCOP 1.73
  
• Family a.4.1.18: SWIRM domain appears in SCOPe 2.05
  
• Family a.4.1.18: SWIRM domain appears in SCOPe 2.07
  
• Family a.4.1.18: SWIRM domain appears in the current release, SCOPe 2.08