SCOPe 2.08: Superfamily a.2.17: Endosomal sorting complex assembly domain

Lineage for Superfamily a.2.17: Endosomal sorting complex assembly domain

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.2: Long alpha-hairpin [46556] (20 superfamilies)
   2 helices; antiparallel hairpin, left-handed twist

4. Superfamily a.2.17: Endosomal sorting complex assembly domain [140111] (4 families)
   forms 'fan'-like heterooligomers, in which the domains of different subunit make similar interactions at the tip of the hairpin

Families:

1. a.2.17.1: VPS23 C-terminal domain [140112] (1 protein)
   automatically mapped to Pfam PF09454

2. a.2.17.2: VPS28 N-terminal domain [140115] (2 proteins)
   includes structurally variable linker region

3. a.2.17.3: VPS37 C-terminal domain-like [140118] (1 protein)
   Pfam PF07200; Modifier of rudimentary, Mod(r)

4. a.2.17.0: automated matches [385867] (1 protein)
   not a true family

More info for Superfamily a.2.17: Endosomal sorting complex assembly domain

Timeline for Superfamily a.2.17: Endosomal sorting complex assembly domain:

• Superfamily a.2.17: Endosomal sorting complex assembly domain first appeared in SCOP 1.73
  
• Superfamily a.2.17: Endosomal sorting complex assembly domain appears in SCOPe 2.07