SCOP 1.73: Domain d2v0md1: 2v0m D:30-496

Lineage for d2v0md1 (2v0m D:30-496)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (1 family)

5. Family a.104.1.1: Cytochrome P450 [48265] (21 proteins)

6. Protein Mammalian cytochrome P450 3a4 [109958] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109959] (6 PDB entries)

8. Domain d2v0md1: 2v0m D:30-496 [140053]
   complexed with hem, kln

Details for d2v0md1

PDB Entry: 2v0m, 3.8 Å

PDB Description: crystal structure of human p450 3a4 in complex with ketoconazole

PDB Compounds: (D:) cytochrome p450 3a4

SCOP Domain Sequences for d2v0md1:

Sequence, based on SEQRES records:

>d2v0md1 a.104.1.1 (D:30-496) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdpdm
iktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvpii
aqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfventkk
llrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledtqkhrv
dflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimyelathpdvqq
klqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfip
kgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfal
mnmklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesr

Sequence, based on observed residues (ATOM records):

>d2v0md1 a.104.1.1 (D:30-496) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdpdm
iktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvpii
aqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfventkk
llrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledvdflql
midsqalsdlelvaqsiififagyettssvlsfimyelathpdvqqklqeeidavlpnka
pptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfipkgvvvmipsyalhr
dpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfalmnmklalirvlqnf
sfkpcketqiplklslggllqpekpvvlkvesr

Timeline for d2v0md1:

• d2v0md1 is new in SCOP 1.73
  
• d2v0md1 appears in SCOP 1.75
  
• d2v0md1 appears in the current release, SCOPe 2.08