SCOPe 2.05: Domain d2uwob_: 2uwo B:

Lineage for d2uwob_ (2uwo B:)

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Factor X, N-terminal module [57205] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57206] (83 PDB entries)
   Uniprot P00742 127-178

8. Domain d2uwob_: 2uwo B: [139999]
   Other proteins in same PDB: d2uwoa_
   automated match to d1lpga_
   complexed with 701

Details for d2uwob_

PDB Entry: 2uwo, 1.75 Å

PDB Description: selective and dual action orally active inhibitors of thrombin and factor xa

PDB Compounds: (B:) coagulation factor x

SCOPe Domain Sequences for d2uwob_:

Sequence; same for both SEQRES and ATOM records:

>d2uwob_ g.3.11.1 (B:) Factor X, N-terminal module {Human (Homo sapiens) [TaxId: 9606]}
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtl

Timeline for d2uwob_:

• d2uwob_ first appeared in SCOP 1.73, called d2uwob1
  
• d2uwob_ appears in SCOPe 2.04
  
• d2uwob_ appears in SCOPe 2.06
  
• d2uwob_ appears in the current release, SCOPe 2.08