Lineage for d2uwoa1 (2uwo A:16-244)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 670182Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 670183Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) (S)
  5. 670328Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)
  6. 670527Protein Coagulation factor Xa, protease domain [50574] (2 species)
  7. 670530Species Human (Homo sapiens) [TaxId:9606] [50575] (58 PDB entries)
  8. 670534Domain d2uwoa1: 2uwo A:16-244 [139998]
    Other proteins in same PDB: d2uwob1
    automatically matched to d1c5md_
    complexed with 701

Details for d2uwoa1

PDB Entry: 2uwo (more details), 1.75 Å

PDB Description: selective and dual action orally active inhibitors of thrombin and factor xa
PDB Compounds: (A:) coagulation factor x

SCOP Domain Sequences for d2uwoa1:

Sequence, based on SEQRES records: (download)

>d2uwoa1 b.47.1.2 (A:16-244) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Sequence, based on observed residues (ATOM records): (download)

>d2uwoa1 b.47.1.2 (A:16-244) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qegeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtq
ktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacq
gdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

SCOP Domain Coordinates for d2uwoa1:

Click to download the PDB-style file with coordinates for d2uwoa1.
(The format of our PDB-style files is described here.)

Timeline for d2uwoa1: