SCOP 1.73: Domain d2uwlb1: 2uwl B:-2-49

Lineage for d2uwlb1 (2uwl B:-2-49)

1. Root: SCOP 1.73

2. Class g: Small proteins [56992] (85 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (7 families)

5. Family g.3.11.1: EGF-type module [57197] (22 proteins)

6. Protein Factor X, N-terminal module [57205] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57206] (59 PDB entries)

8. Domain d2uwlb1: 2uwl B:-2-49 [139991]
   Other proteins in same PDB: d2uwla1
   automatically matched to d1g2lb_
   complexed with 895

Details for d2uwlb1

PDB Entry: 2uwl, 1.9 Å

PDB Description: selective and dual action orally active inhibitors of thrombin and factor xa

PDB Compounds: (B:) coagulation factor x

SCOP Domain Sequences for d2uwlb1:

Sequence; same for both SEQRES and ATOM records:

>d2uwlb1 g.3.11.1 (B:-2-49) Factor X, N-terminal module {Human (Homo sapiens) [TaxId: 9606]}
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtl

Timeline for d2uwlb1:

• d2uwlb1 is new in SCOP 1.73
  
• d2uwlb1 appears in SCOP 1.75
  
• d2uwlb1 appears in the current release, SCOPe 2.08, called d2uwlb_