SCOP 1.73: Domain d2q4ra1: 2q4r A:4-246

Lineage for d2q4ra1 (2q4r A:4-246)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (23 families)
   usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.10: Predicted hydrolases Cof [82388] (11 proteins)
   contains an alpha+beta subdomain inserted into a new site after strand 3

6. Protein Phosphomannomutase 2 [142159] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142160] (2 PDB entries)

8. Domain d2q4ra1: 2q4r A:4-246 [139876]
   automatically matched to 2AMY A:4-246
   complexed with edo, gly

Details for d2q4ra1

PDB Entry: 2q4r, 2.09 Å

PDB Description: Ensemble refinement of the protein crystal structure of human phosphomannomutase 2 (PMM2)

PDB Compounds: (A:) Phosphomannomutase 2

SCOP Domain Sequences for d2q4ra1:

Sequence, based on SEQRES records:

>d2q4ra1 c.108.1.10 (A:4-246) Phosphomannomutase 2 {Human (Homo sapiens) [TaxId: 9606]}
pgpalclfdvdgtltaprqkitkemddflqklrqkikigvvggsdfekvqeqlgndvvek
ydyvfpenglvaykdgkllcrqniqshlgealiqdlinyclsyiakiklpkkrgtfiefr
ngmlnvspigrscsqeeriefyeldkkenirqkfvadlrkefagkgltfsiggqisfdvf
pdgwdkryclrhvendgyktiyffgdktmpggndheiftdprtmgysvtapedtrricel
lfs

Sequence, based on observed residues (ATOM records):

>d2q4ra1 c.108.1.10 (A:4-246) Phosphomannomutase 2 {Human (Homo sapiens) [TaxId: 9606]}
pgpalclfdvdgtltaprqkitkemddflqklrqkikigvvggsdfekvqeqlgndvvek
ydyvfpenglvaykdgkllcrqniqshlgealiqdlinyclsyiakiklpkkrgtfiefr
ngmlnvspigrscsqeeriefyeldkkenirqkfvadlrkefagkgltfsiggqisfdvf
pdgwdkryclrhvendgyktiyffgdktmndheiftdprtmgysvtapedtrricellfs

Timeline for d2q4ra1:

• d2q4ra1 is new in SCOP 1.73
  
• d2q4ra1 appears in SCOP 1.75
  
• d2q4ra1 appears in the current release, SCOPe 2.08, called d2q4ra_