SCOPe 2.08: Domain d2q4ra_: 2q4r A:

Lineage for d2q4ra_ (2q4r A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (26 families)
   usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.10: Predicted hydrolases Cof [82388] (12 proteins)
   contains an alpha+beta subdomain inserted into a new site after strand 3

6. Protein Phosphomannomutase 2 [142159] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142160] (2 PDB entries)
   Uniprot O15305 4-246

8. Domain d2q4ra_: 2q4r A: [139876]
   automated match to d2amya1
   complexed with edo, gly

Details for d2q4ra_

PDB Entry: 2q4r, 2.09 Å

PDB Description: Ensemble refinement of the protein crystal structure of human phosphomannomutase 2 (PMM2)

PDB Compounds: (A:) Phosphomannomutase 2

SCOPe Domain Sequences for d2q4ra_:

Sequence, based on SEQRES records:

>d2q4ra_ c.108.1.10 (A:) Phosphomannomutase 2 {Human (Homo sapiens) [TaxId: 9606]}
pgpalclfdvdgtltaprqkitkemddflqklrqkikigvvggsdfekvqeqlgndvvek
ydyvfpenglvaykdgkllcrqniqshlgealiqdlinyclsyiakiklpkkrgtfiefr
ngmlnvspigrscsqeeriefyeldkkenirqkfvadlrkefagkgltfsiggqisfdvf
pdgwdkryclrhvendgyktiyffgdktmpggndheiftdprtmgysvtapedtrricel
lfs

Sequence, based on observed residues (ATOM records):

>d2q4ra_ c.108.1.10 (A:) Phosphomannomutase 2 {Human (Homo sapiens) [TaxId: 9606]}
pgpalclfdvdgtltaprqkitkemddflqklrqkikigvvggsdfekvqeqlgndvvek
ydyvfpenglvaykdgkllcrqniqshlgealiqdlinyclsyiakiklpkkrgtfiefr
ngmlnvspigrscsqeeriefyeldkkenirqkfvadlrkefagkgltfsiggqisfdvf
pdgwdkryclrhvendgyktiyffgdktmndheiftdprtmgysvtapedtrricellfs

Timeline for d2q4ra_:

• d2q4ra_ first appeared in SCOP 1.73, called d2q4ra1
  
• d2q4ra_ appears in SCOPe 2.07