Lineage for d2pw2b2 (2pw2 B:114-214)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 654118Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 655111Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)
  7. 655115Species Human (Homo sapiens) [TaxId:9606] [88575] (150 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
  8. 655262Domain d2pw2b2: 2pw2 B:114-214 [139761]
    Other proteins in same PDB: d2pw2b1
    automatically matched to d2f5ah2

Details for d2pw2b2

PDB Entry: 2pw2 (more details), 2.55 Å

PDB Description: Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWKSL
PDB Compounds: (B:) 2F5 Fab' light chain

SCOP Domain Sequences for d2pw2b2:

Sequence, based on SEQRES records: (download)

>d2pw2b2 b.1.1.2 (B:114-214) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
tstkgpsvfplapsskstaggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvep

Sequence, based on observed residues (ATOM records): (download)

>d2pw2b2 b.1.1.2 (B:114-214) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
tstkgpsvfplaptaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpsssqtytcnvnhkpsntkvdkrvep

SCOP Domain Coordinates for d2pw2b2:

Click to download the PDB-style file with coordinates for d2pw2b2.
(The format of our PDB-style files is described here.)

Timeline for d2pw2b2: