SCOPe 2.05: Domain d2pvwa1: 2pvw A:594-750

Lineage for d2pvwa1 (2pvw A:594-750)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.48: N-cbl like [47667] (5 superfamilies)
   4 helices; bundle, left-handed twist; left-handed superhelix

4. Superfamily a.48.2: Transferrin receptor-like dimerisation domain [47672] (1 family)
   automatically mapped to Pfam PF04253

5. Family a.48.2.1: Transferrin receptor-like dimerisation domain [47673] (2 proteins)

6. Protein Glutamate carboxypeptidase II [140574] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [140575] (23 PDB entries)
   Uniprot Q04609 594-750

8. Domain d2pvwa1: 2pvw A:594-750 [139755]
   Other proteins in same PDB: d2pvwa2, d2pvwa3
   automatically matched to 2C6C A:594-750
   complexed with ca, cl, g88, nag, zn

Details for d2pvwa1

PDB Entry: 2pvw, 1.71 Å

PDB Description: a high resolution structure of human glutamate carboxypeptidase ii (gcpii) in complex with 2-(phosphonomethyl)pentanedioic acid (2-pmpa)

PDB Compounds: (A:) glutamate carboxypeptidase 2

SCOPe Domain Sequences for d2pvwa1:

Sequence, based on SEQRES records:

>d2pvwa1 a.48.2.1 (A:594-750) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
pfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdf
dksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalf
dieskvdpskawgevkrqiyvaaftvqaaaetlseva

Sequence, based on observed residues (ATOM records):

>d2pvwa1 a.48.2.1 (A:594-750) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
pfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdf
snpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalfdi
eskvdpskawgevkrqiyvaaftvqaaaetlseva

Timeline for d2pvwa1:

• d2pvwa1 first appeared in SCOP 1.73
  
• d2pvwa1 appears in SCOPe 2.04
  
• d2pvwa1 appears in SCOPe 2.06
  
• d2pvwa1 appears in the current release, SCOPe 2.08