Lineage for d2peva1 (2pev A:0-315)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 681098Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 681974Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (1 family) (S)
  5. 681975Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (15 proteins)
    Common fold covers whole protein structure
  6. 682015Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 682016Species Human (Homo sapiens) [TaxId:9606] [51437] (53 PDB entries)
  8. 682023Domain d2peva1: 2pev A:0-315 [139669]
    automatically matched to d1pwla_
    complexed with cit, cl, fid, ldt, ndp

Details for d2peva1

PDB Entry: 2pev (more details), 0.9 Å

PDB Description: Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution exceeds concentration of IDD594.
PDB Compounds: (A:) aldose reductase

SCOP Domain Sequences for d2peva1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2peva1 c.1.7.1 (A:0-315) Aldose reductase (aldehyde reductase) {Human (Homo sapiens) [TaxId: 9606]}

SCOP Domain Coordinates for d2peva1:

Click to download the PDB-style file with coordinates for d2peva1.
(The format of our PDB-style files is described here.)

Timeline for d2peva1: