SCOPe 2.08: Domain d2p66a3: 2p66 A:149-335

Lineage for d2p66a3 (2p66 A:149-335)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (5 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein DNA polymerase beta, catalytic (31 kD) fragment [81578] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81574] (145 PDB entries)
   Uniprot P06746

8. Domain d2p66a3: 2p66 A:149-335 [139508]
   Other proteins in same PDB: d2p66a1, d2p66a2
   automated match to d1tv9a3
   protein/DNA complex; complexed with na, po4

Details for d2p66a3

PDB Entry: 2p66, 2.5 Å

PDB Description: Human DNA Polymerase beta complexed with tetrahydrofuran (abasic site) containing DNA

PDB Compounds: (A:) DNA polymerase beta

SCOPe Domain Sequences for d2p66a3:

Sequence, based on SEQRES records:

>d2p66a3 d.218.1.2 (A:149-335) DNA polymerase beta, catalytic (31 kD) fragment {Human (Homo sapiens) [TaxId: 9606]}
ripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessgdmdvllthpsftsestkqp
kllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndekeyphrridirlipkdqyycg
vlyftgsdifnknmrahalekgftineytirplgvtgvageplpvdsekdifdyiqwkyr
epkdrse

Sequence, based on observed residues (ATOM records):

>d2p66a3 d.218.1.2 (A:149-335) DNA polymerase beta, catalytic (31 kD) fragment {Human (Homo sapiens) [TaxId: 9606]}
ripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessgdmdvllthpsftsespkll
hqvveqlqkvhfitdtlskgetkfmgvcqlpskndekeyphrridirlipkdqyycgvly
ftgsdifnknmrahalekgftineytirplgvtgvageplpvdsekdifdyiqwkyrepk
drse

Timeline for d2p66a3:

• d2p66a3 first appeared in SCOP 1.73
  
• d2p66a3 appears in SCOPe 2.07