SCOPe 2.06: Domain d2p54a_: 2p54 A:

Lineage for d2p54a_ (2p54 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69110] (16 PDB entries)

8. Domain d2p54a_: 2p54 A: [139497]
   automated match to d1i7ga_
   complexed with 735

Details for d2p54a_

PDB Entry: 2p54, 1.79 Å

PDB Description: a crystal structure of PPAR alpha bound with SRC1 peptide and GW735

PDB Compounds: (A:) Peroxisome proliferator-activated receptor alpha

SCOPe Domain Sequences for d2p54a_:

Sequence; same for both SEQRES and ATOM records:

>d2p54a_ a.123.1.1 (A:) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
dlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvaklvan
giqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifaml
ssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfvaa
iiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvteha
qlvqiikktesdaalhpllqeiyrdmy

Timeline for d2p54a_:

• d2p54a_ first appeared in SCOP 1.73, called d2p54a1
  
• d2p54a_ appears in SCOPe 2.05
  
• d2p54a_ appears in SCOPe 2.07
  
• d2p54a_ appears in the current release, SCOPe 2.08