SCOPe 2.08: Domain d2p2la_: 2p2l A:

Lineage for d2p2la_ (2p2l A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rac [52595] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52596] (41 PDB entries)

8. Domain d2p2la_: 2p2l A: [139465]
   automated match to d1hh4a_
   complexed with gdp, zn

Details for d2p2la_

PDB Entry: 2p2l, 1.9 Å

PDB Description: rac1-gdp-zinc complex

PDB Compounds: (A:) ras-related c3 botulinum toxin substrate 1

SCOPe Domain Sequences for d2p2la_:

Sequence, based on SEQRES records:

>d2p2la_ c.37.1.8 (A:) Rac {Human (Homo sapiens) [TaxId: 9606]}
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcp

Sequence, based on observed residues (ATOM records):

>d2p2la_ c.37.1.8 (A:) Rac {Human (Homo sapiens) [TaxId: 9606]}
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvgkpvnlglwdtagqed
ydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlrddk
dtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcp

Timeline for d2p2la_:

• d2p2la_ first appeared in SCOP 1.73, called d2p2la1
  
• d2p2la_ appears in SCOPe 2.07