SCOPe 2.08: Domain d2oz5a_: 2oz5 A:

Lineage for d2oz5a_ (2oz5 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.5: Mycobacterial PtpB-like [142348] (1 protein)

6. Protein Phosphotyrosine protein phosphatase PtpB [142349] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [142350] (2 PDB entries)
   Uniprot P96830 4-275

8. Domain d2oz5a_: 2oz5 A: [139439]
   automated match to d1ywfa1
   complexed with 7xy

Details for d2oz5a_

PDB Entry: 2oz5, 2 Å

PDB Description: crystal structure of mycobacterium tuberculosis protein tyrosine phosphatase ptpb in complex with the specific inhibitor omts

PDB Compounds: (A:) phosphotyrosine protein phosphatase ptpb

SCOPe Domain Sequences for d2oz5a_:

Sequence, based on SEQRES records:

>d2oz5a_ c.45.1.5 (A:) Phosphotyrosine protein phosphatase PtpB {Mycobacterium tuberculosis [TaxId: 1773]}
relpgawnfrdvadtatalrpgrlfrsselsrlddagratlrrlgitdvadlrssrevar
rgpgrvpdgidvhllpfpdladddaddsaphetafkrlltndgsngesgessqsindaat
rymtdeyrqfptrngaqralhrvvtllaagrpvlthcfagkdrtgfvvalvleavgldrd
vivadylrsndsvpqlrarisemiqqrfdtelapevvtftkarlsdgvlgvraeylaaar
qtidetygslggylrdagisqatvnrmrgvllg

Sequence, based on observed residues (ATOM records):

>d2oz5a_ c.45.1.5 (A:) Phosphotyrosine protein phosphatase PtpB {Mycobacterium tuberculosis [TaxId: 1773]}
relpgawnfrdvadtatalrpgrlfrsselsrlddagratlrrlgitdvadlrssrevar
rgpgrvpdgidvhllpfpdladdaddsaphetafkrlltngessqsindaatrymtdeyr
qfptrngaqralhrvvtllaagrpvlthcfagkdrtgfvvalvleavgldrdvivadylr
sndsvpqlrarisemiqqrfdtelapevvtftkarlsdgvlgvraeylaaarqtidetyg
slggylrdagisqatvnrmrgvllg

Timeline for d2oz5a_:

• d2oz5a_ first appeared in SCOP 1.73, called d2oz5a1
  
• d2oz5a_ appears in SCOPe 2.07