SCOPe 2.05: Domain d2ovma_: 2ovm A:

Lineage for d2ovma_ (2ovm A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Progesterone receptor [48517] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48518] (10 PDB entries)
   Uniprot P06401 679-932

8. Domain d2ovma_: 2ovm A: [139381]
   automated match to d1a28a_
   complexed with as0

Details for d2ovma_

PDB Entry: 2ovm, 2.6 Å

PDB Description: progesterone receptor with bound asoprisnil and a peptide from the co- repressor ncor

PDB Compounds: (A:) progesterone receptor

SCOPe Domain Sequences for d2ovma_:

Sequence, based on SEQRES records:

>d2ovma_ a.123.1.1 (A:) Progesterone receptor {Human (Homo sapiens) [TaxId: 9606]}
qlipplinllmsiepdviyaghdntkpdtssslltslnqlgerqllsvvkwskslpgfrn
lhiddqitliqyswmslmvfglgwrsykhvsgqmlyfapdlilneqrmkessfyslcltm
wqipqefvklqvsqeeflcmkvllllntipleglrsqtqfeemrssyirelikaiglrqk
gvvsssqrfyqltklldnlhdlvkqlhlyclntfiqsralsvefpemmseviaaqlpkil
agmvkpllfhk

Sequence, based on observed residues (ATOM records):

>d2ovma_ a.123.1.1 (A:) Progesterone receptor {Human (Homo sapiens) [TaxId: 9606]}
qlipplinllmsiepdviyaghdntkpdtssslltslnqlgerqllsvvkwskslpgfrn
lhiddqitliqyswmslmvfglgwrsykhvsgqmlyfapdlilneqrmkessfyslcltm
wqipqefvklqvsqeeflcmkvllllntipleglrsqtqfeemrssyirelikaiglrqk
gvvsssqrfyqltklldnlhdlvkqlhlyclntfiqsramseviaaqlpkilagmvkpll
fhk

Timeline for d2ovma_:

• d2ovma_ first appeared in SCOP 1.73, called d2ovma1
  
• d2ovma_ appears in SCOPe 2.04
  
• d2ovma_ appears in SCOPe 2.06
  
• d2ovma_ appears in the current release, SCOPe 2.08