SCOPe 2.05: Domain d2ovha_: 2ovh A:

Lineage for d2ovha_ (2ovh A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Progesterone receptor [48517] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48518] (10 PDB entries)
   Uniprot P06401 679-932

8. Domain d2ovha_: 2ovh A: [139380]
   automated match to d1a28a_
   complexed with as0

Details for d2ovha_

PDB Entry: 2ovh, 2 Å

PDB Description: progesterone receptor with bound asoprisnil and a peptide from the co- repressor smrt

PDB Compounds: (A:) progesterone receptor

SCOPe Domain Sequences for d2ovha_:

Sequence, based on SEQRES records:

>d2ovha_ a.123.1.1 (A:) Progesterone receptor {Human (Homo sapiens) [TaxId: 9606]}
iqlipplinllmsiepdviyaghdntkpdtssslltslnqlgerqllsvvkwskslpgfr
nlhiddqitliqyswmslmvfglgwrsykhvsgqmlyfapdlilneqrmkessfyslclt
mwqipqefvklqvsqeeflcmkvllllntipleglrsqtqfeemrssyirelikaiglrq
kgvvsssqrfyqltklldnlhdlvkqlhlyclntfiqsralsvefpemmseviaaqlpki
lagmvkpllfhk

Sequence, based on observed residues (ATOM records):

>d2ovha_ a.123.1.1 (A:) Progesterone receptor {Human (Homo sapiens) [TaxId: 9606]}
iqlipplinllmsiepdviyaghdntkpdtssslltslnqlgerqllsvvkwskslpgfr
nlhiddqitliqyswmslmvfglgwrsykhvsgqmlyfapdlilneqrmkessfyslclt
mwqipqefvklqvsqeeflcmkvllllntipleglrsqtqfeemrssyirelikaiglrq
kgvvsssqrfyqltklldnlhdlvkqlhlyclntfiqsrmseviaaqlpkilagmvkpll
fhk

Timeline for d2ovha_:

• d2ovha_ first appeared in SCOP 1.73, called d2ovha1
  
• d2ovha_ appears in SCOPe 2.04
  
• d2ovha_ appears in SCOPe 2.06
  
• d2ovha_ appears in the current release, SCOPe 2.08