SCOPe 2.06: Domain d2ouza_: 2ouz A:

Lineage for d2ouza_ (2ouz A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (64 PDB entries)
   Uniprot P03372 307-551

8. Domain d2ouza_: 2ouz A: [139378]
   automated match to d1qkua_
   complexed with c3d

Details for d2ouza_

PDB Entry: 2ouz, 2 Å

PDB Description: crystal structure of estrogen receptor alpha-lasofoxifene complex

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d2ouza_:

Sequence; same for both SEQRES and ATOM records:

>d2ouza_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemld
ahrlha

Timeline for d2ouza_:

• d2ouza_ first appeared in SCOP 1.73, called d2ouza1
  
• d2ouza_ appears in SCOPe 2.05
  
• d2ouza_ appears in SCOPe 2.07
  
• d2ouza_ appears in the current release, SCOPe 2.08