SCOP 1.75: Domain d2otxa1: 2otx A:14-222

Lineage for d2otxa1 (2otx A:14-222)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (13 families)

5. Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (47 proteins)
   Pfam PF00169

6. Protein Src-associated adaptor protein Skap2 [141417] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [141418] (4 PDB entries)
   Uniprot Q9Z2K4 105-212! Uniprot Q9Z2K4 109-219! Uniprot Q9Z2K4 14-222

8. Domain d2otxa1: 2otx A:14-222 [139373]
   automatically matched to 1U5E A:14-222
   mutant

Details for d2otxa1

PDB Entry: 2otx, 2.6 Å

PDB Description: crystal structure of a n-terminal fragment of skap-hom containing both the helical dimerization domain and the ph domain

PDB Compounds: (A:) Src kinase-associated phosphoprotein 2

SCOP Domain Sequences for d2otxa1:

Sequence, based on SEQRES records:

>d2otxa1 b.55.1.1 (A:14-222) Src-associated adaptor protein Skap2 {Mouse (Mus musculus) [TaxId: 10090]}
peeirnlladvetfvadtlkgenlskkakekreslikkikdvksvylqefqdkgdaedgd
eyddpfagpadtislaserydkdddgpsdgnqfppiaaqdlpfvikagylekrrkdhsfl
gfewqkrwcalsktvfyyygsdkdkqqkgefaidgydvrmnntlrkdgkkdccfeicapd
kriyqftaaspkdaeewvqqlkfilqdlg

Sequence, based on observed residues (ATOM records):

>d2otxa1 b.55.1.1 (A:14-222) Src-associated adaptor protein Skap2 {Mouse (Mus musculus) [TaxId: 10090]}
peeirnlladvetfvadtlkgenlskkakekreslikkikdvksvylqefqfppiaaqdl
pfvikagylekrrkdhsflgfewqkrwcalsktvfyyygsdkdkqqkgefaidgydvrmn
ntlrkdgkkdccfeicapdkriyqftaaspkdaeewvqqlkfilqdlg

Timeline for d2otxa1:

• d2otxa1 first appeared in SCOP 1.73
  
• d2otxa1 is called d2otxa_ in SCOPe 2.01
  
• d2otxa1 appears in the current release, SCOPe 2.08, called d2otxa_