SCOP 1.73: Domain d2ot1b1: 2ot1 B:1-363

Lineage for d2ot1b1 (2ot1 B:1-363)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (8 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (12 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein Fructose-1,6-bisphosphate aldolase [51576] (10 species)

7. Species Rabbit (Oryctolagus cuniculus), muscle isozyme [TaxId:9986] [51580] (13 PDB entries)

8. Domain d2ot1b1: 2ot1 B:1-363 [139308]
   automatically matched to 1ZAH A:1-363
   complexed with n3p

Details for d2ot1b1

PDB Entry: 2ot1, 2.05 Å

PDB Description: Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with naphthol AS-E phosphate, a competitive inhibitor

PDB Compounds: (B:) Fructose-bisphosphate aldolase A

SCOP Domain Sequences for d2ot1b1:

Sequence, based on SEQRES records:

>d2ot1b1 c.1.10.1 (B:1-363) Fructose-1,6-bisphosphate aldolase {Rabbit (Oryctolagus cuniculus), muscle isozyme [TaxId: 9986]}
phshpaltpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyrq
llltaddrvnpciggvilfhetlyqkaddgrpfpqvikskggvvgikvdkgvvplagtng
etttqgldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqn
givpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghact
qkysheeiamatvtalrrtvppavtgvtflsggqseeeasinlnainkcpllkpwaltfs
ygralqasalkawggkkenlkaaqeeyvkralanslacqgkytpsgqagaaaseslfisn
hay

Sequence, based on observed residues (ATOM records):

>d2ot1b1 c.1.10.1 (B:1-363) Fructose-1,6-bisphosphate aldolase {Rabbit (Oryctolagus cuniculus), muscle isozyme [TaxId: 9986]}
phshpaltpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyrq
llltaddrvnpciggvilfhetlyqkaddgrpfpqvikskggvvgikvdkgvvplagtng
etttqgldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqn
givpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghact
qkysheeiamatvtalrrtvppavtgvtflsggqseeeasinlnainkcpllkpwaltfs
ygralqasalkawggkkenlkaaqeeyvkralanslacqgkytpssnhay

Timeline for d2ot1b1:

• d2ot1b1 is new in SCOP 1.73
  
• d2ot1b1 appears in SCOP 1.75
  
• d2ot1b1 appears in the current release, SCOPe 2.08, called d2ot1b_