SCOPe 2.08: Domain d2oj9a_: 2oj9 A:

Lineage for d2oj9a_ (2oj9 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin-like growth factor 1 receptor [69825] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [69826] (18 PDB entries)

8. Domain d2oj9a_: 2oj9 A: [139102]
   automated match to d1m7na_
   complexed with bmi

Details for d2oj9a_

PDB Entry: 2oj9, 2 Å

PDB Description: Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor

PDB Compounds: (A:) Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen)

SCOPe Domain Sequences for d2oj9a_:

Sequence, based on SEQRES records:

>d2oj9a_ d.144.1.7 (A:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
advyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmre
rieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpv
lappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyet
dyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlr
fvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyse
enk

Sequence, based on observed residues (ATOM records):

>d2oj9a_ d.144.1.7 (A:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
advyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmre
rieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpeppslsk
miqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggk
gllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmeggll
dkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

Timeline for d2oj9a_:

• d2oj9a_ first appeared in SCOP 1.73, called d2oj9a1
  
• d2oj9a_ appears in SCOPe 2.07