SCOPe 2.05: Domain d2o2ya_: 2o2y A:

Lineage for d2o2ya_ (2o2y A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Enoyl-ACP reductase [51791] (11 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [82296] (23 PDB entries)
   Uniprot Q9BJJ9 96-424 # fragment

8. Domain d2o2ya_: 2o2y A: [138894]
   automated match to d1uh5a_
   complexed with cl, nad, so4, tcl

Details for d2o2ya_

PDB Entry: 2o2y, 2.2 Å

PDB Description: The crystal structure of P. falciparum enoyl acyl carrier protein reductase

PDB Compounds: (A:) enoyl-acyl carrier reductase

SCOPe Domain Sequences for d2o2ya_:

Sequence, based on SEQRES records:

>d2o2ya_ c.2.1.2 (A:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
dicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkdk
kmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsla
nakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpgy
gggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntnqn
knrnshdvhnimnnsgekeekknsasqnytfidyaieysekyaplrqkllstdigsvasf
llsresraitgqtiyvdnglnimflpddiyr

Sequence, based on observed residues (ATOM records):

>d2o2ya_ c.2.1.2 (A:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
dicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkdk
kmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsla
nakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpgy
gggmssakaalesdtrvlayhlgrnynirintisagplksraatainytfidyaieysek
yaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpddiyr

Timeline for d2o2ya_:

• d2o2ya_ first appeared in SCOP 1.73, called d2o2ya1
  
• d2o2ya_ appears in SCOPe 2.04
  
• d2o2ya_ appears in SCOPe 2.06
  
• d2o2ya_ appears in the current release, SCOPe 2.08