Lineage for d2o23b_ (2o23 B:)

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1150729Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 1150730Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 1151047Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 1152087Protein automated matches [190085] (34 species)
    not a true protein
  7. 1152174Species Human (Homo sapiens) [TaxId:9606] [186828] (5 PDB entries)
  8. 1152176Domain d2o23b_: 2o23 B: [138885]
    automated match to d1u7ta_
    complexed with gol, nad

Details for d2o23b_

PDB Entry: 2o23 (more details), 1.2 Å

PDB Description: the structure of wild-type human hadh2 (17beta-hydroxysteroid dehydrogenase type 10) bound to nad+ at 1.2 a
PDB Compounds: (B:) HADH2 protein

SCOPe Domain Sequences for d2o23b_:

Sequence, based on SEQRES records: (download)

>d2o23b_ c.2.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
maaacrsvkglvavitggasglglataerlvgqgasavlldlpnsggeaqakklgnncvf
apadvtsekdvqtalalakgkfgrvdvavncagiavasktynlkkgqthtledfqrvldv
nlmgtfnvirlvagemgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtl
piardlapigirvmtiapglfgtplltslpekvcnflasqvpfpsrlgdpaeyahlvqai
ienpflngevirldgairmqpgs

Sequence, based on observed residues (ATOM records): (download)

>d2o23b_ c.2.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
maaacrsvkglvavitggasglglataerlvgqgasavlldlpnsggeaqakklgnncvf
apadvtsekdvqtalalakgkfgrvdvavncagiavasktynlkkgqthtledfqrvldv
nlmgtfnvirlvagemgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtl
piardlapigirvmtiapglfgtpllnflasqvpfpsrlgdpaeyahlvqaiienpflng
evirldgairmqpgs

SCOPe Domain Coordinates for d2o23b_:

Click to download the PDB-style file with coordinates for d2o23b_.
(The format of our PDB-style files is described here.)

Timeline for d2o23b_: