Lineage for d2o21a_ (2o21 A:)

  1. Root: SCOPe 2.08
  2. 3021034Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)
  3. 3021035Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 3021129Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 3021130Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 3021262Protein Bcl-2 [64524] (1 species)
  7. 3021263Species Human (Homo sapiens) [TaxId:9606] [64525] (18 PDB entries)
  8. 3021288Domain d2o21a_: 2o21 A: [138882]
    automated match to d1gjha_
    complexed with 43b

    has additional insertions and/or extensions that are not grouped together

Details for d2o21a_

PDB Entry: 2o21 (more details)

PDB Description: solution structure of the anti-apoptotic protein bcl-2 in complex with an acyl-sulfonamide-based ligand
PDB Compounds: (A:) Apoptosis regulator Bcl-2

SCOPe Domain Sequences for d2o21a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2o21a_ f.1.4.1 (A:) Bcl-2 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2o21a_:

Click to download the PDB-style file with coordinates for d2o21a_.
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Timeline for d2o21a_: