SCOP 1.73: Domain d2o07a1: 2o07 A:16-300

Lineage for d2o07a1 (2o07 A:16-300)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (52 families)

5. Family c.66.1.17: Spermidine synthase [69557] (2 proteins)
   contains additional N-terminal tetramerisation all-beta domain, res. 1-71

6. Protein Spermidine synthase [69558] (6 species)
   polyamine aminopropyltransferase

7. Species Human (Homo sapiens) [TaxId:9606] [142590] (4 PDB entries)

8. Domain d2o07a1: 2o07 A:16-300 [138862]
   automatically matched to 2O05 A:15-300
   complexed with mta, spd

Details for d2o07a1

PDB Entry: 2o07, 1.89 Å

PDB Description: Human spermidine synthase

PDB Compounds: (A:) spermidine synthase

SCOP Domain Sequences for d2o07a1:

Sequence, based on SEQRES records:

>d2o07a1 c.66.1.17 (A:16-300) Spermidine synthase {Human (Homo sapiens) [TaxId: 9606]}
iregwfretcslwpgqalslqveqllhhrrsryqdilvfrsktygnvlvldgviqcterd
efsyqemianlplcshpnprkvliigggdggvlrevvkhpsvesvvqceidedviqvskk
flpgmaigyssskltlhvgdgfefmkqnqdafdviitdssdpmgpaeslfkesyyqlmkt
alkedgvlccqgecqwlhldlikemrqfcqslfpvvayayctiptypsgqigfmlcsknp
stnfqepvqpltqqqvaqmqlkyynsdvhraafvlpefarkalnd

Sequence, based on observed residues (ATOM records):

>d2o07a1 c.66.1.17 (A:16-300) Spermidine synthase {Human (Homo sapiens) [TaxId: 9606]}
iregwfretcslwpgqalslqveqllhhrrsryqdilvfrsktygnvlvldgviqcterd
efsyqemianlplcshpnprkvliigggdggvlrevvkhpsvesvvqceidedviqvskk
flpgmaigyssskltlhvgdgfefmkqnqdafdviitdssesyyqlmktalkedgvlccq
gecqwlhldlikemrqfcqslfpvvayayctiptypsgqigfmlcsknpstnfqepvqpl
tqqqvaqmqlkyynsdvhraafvlpefarkalnd

Timeline for d2o07a1:

• d2o07a1 is new in SCOP 1.73
  
• d2o07a1 appears in SCOP 1.75
  
• d2o07a1 appears in the current release, SCOPe 2.08, called d2o07a_