Lineage for d2nxzd1 (2nxz D:3001-3128)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2739730Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2739829Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88544] (37 PDB entries)
  8. 2739848Domain d2nxzd1: 2nxz D:3001-3128 [138755]
    Other proteins in same PDB: d2nxza1, d2nxzb1, d2nxzb2, d2nxzc1, d2nxzc2, d2nxzd2
    automated match to d1rzjh1
    complexed with edo, hez, ipa, nag

Details for d2nxzd1

PDB Entry: 2nxz (more details), 2.04 Å

PDB Description: hiv-1 gp120 envelope glycoprotein (t257s, s334a, s375w) complexed with cd4 and antibody 17b
PDB Compounds: (D:) antibody 17b, heavy chain

SCOPe Domain Sequences for d2nxzd1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2nxzd1 b.1.1.1 (D:3001-3128) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 1 [TaxId: 9606]}

SCOPe Domain Coordinates for d2nxzd1:

Click to download the PDB-style file with coordinates for d2nxzd1.
(The format of our PDB-style files is described here.)

Timeline for d2nxzd1: