SCOPe 2.01: Domain d2nvwa1: 2nvw A:2-154,A:374-457

Lineage for d2nvwa1 (2nvw A:2-154,A:374-457)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein Galactose/lactose metabolism regulatory protein GAL80 [141921] (1 species)

7. Species Yeast (Kluyveromyces lactis) [TaxId:28985] [141922] (2 PDB entries)
   Uniprot Q06433 2-154,374-457

8. Domain d2nvwa1: 2nvw A:2-154,A:374-457 [138665]
   Other proteins in same PDB: d2nvwa2

Details for d2nvwa1

PDB Entry: 2nvw, 2.1 Å

PDB Description: Crystal sctucture of transcriptional regulator Gal80p from kluyveromymes lactis

PDB Compounds: (A:) Galactose/lactose metabolism regulatory protein GAL80

SCOPe Domain Sequences for d2nvwa1:

Sequence, based on SEQRES records:

>d2nvwa1 c.2.1.3 (A:2-154,A:374-457) Galactose/lactose metabolism regulatory protein GAL80 {Yeast (Kluyveromyces lactis) [TaxId: 28985]}
nnnkrsklstvpssrpirvgfvgltsgkswvakthflaiqqlssqfqivalynptlkssl
qtieqlqlkhatgfdslesfaqykdidmivvsvkvpehyevvknilehssqnlnlrylyv
ewalaasvqqaeelysisqqranlqtiiclqgrXynsvvgnilriyesiadyhflgkpes
kssrgpddlfastkfdkqgfrfegfptfkdaiilhrlidavfrsdkeektldvskimi

Sequence, based on observed residues (ATOM records):

>d2nvwa1 c.2.1.3 (A:2-154,A:374-457) Galactose/lactose metabolism regulatory protein GAL80 {Yeast (Kluyveromyces lactis) [TaxId: 28985]}
nnnkrsklstvpssrpirvgfvgltsgkswvakthflaiqqlssqfqivalynptlkssl
qtieqlqlkhatgfdslesfaqykdidmivvsvkvpehyevvknilehssqnlnlrylyv
ewalaasvqqaeelysisqqranlqtiiclqgrXynsvvgnilriyesiadyhflkfdkq
gfrfegfptfkdaiilhrlidavfrsdkeektldvskimi

Timeline for d2nvwa1:

• d2nvwa1 first appeared in SCOP 1.73
  
• d2nvwa1 appears in SCOP 1.75
  
• d2nvwa1 appears in SCOPe 2.02
  
• d2nvwa1 appears in the current release, SCOPe 2.08