SCOPe 2.05: Domain d2nvha_: 2nvh A:

Lineage for d2nvha_ (2nvh A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.2: Interleukin-1 (IL-1) [50362] (6 proteins)

6. Protein Interleukin-1beta [50363] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50364] (25 PDB entries)
   Uniprot P01584 117-269

8. Domain d2nvha_: 2nvh A: [138630]
   automated match to d1iob__
   complexed with so4

Details for d2nvha_

PDB Entry: 2nvh, 1.53 Å

PDB Description: determination of solvent content in cavities in interleukin-1 using experimentally-phased electron density

PDB Compounds: (A:) interleukin-1 beta

SCOPe Domain Sequences for d2nvha_:

Sequence; same for both SEQRES and ATOM records:

>d2nvha_ b.42.1.2 (A:) Interleukin-1beta {Human (Homo sapiens) [TaxId: 9606]}
apvrslnctlrdsqqkslvmsgpyelkalhlqgqdmeqqvvfsmsfvqgeesndkipval
glkeknlylscvlkddkptlqlesvdpknypkkkmekrfvfnkieinnklefesaqfpnw
yistsqaenmpvflggtkggqditdftmqfvs

Timeline for d2nvha_:

• d2nvha_ first appeared in SCOP 1.73, called d2nvha1
  
• d2nvha_ appears in SCOPe 2.04
  
• d2nvha_ appears in SCOPe 2.06
  
• d2nvha_ appears in the current release, SCOPe 2.08