Lineage for d2nsxa2 (2nsx A:78-431)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2434695Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2438500Superfamily c.1.8: (Trans)glycosidases [51445] (15 families) (S)
  5. 2439241Family c.1.8.3: beta-glycanases [51487] (27 proteins)
    consist of a number of sequence families
  6. 2439671Protein Glucosylceramidase, catalytic domain [89473] (1 species)
    acid-beta-glucosidase; glycosyl hydrolase family 30; contains additional beta-domain similar to one found in alpha amylases
  7. 2439672Species Human (Homo sapiens) [TaxId:9606] [89474] (23 PDB entries)
  8. 2439715Domain d2nsxa2: 2nsx A:78-431 [138553]
    Other proteins in same PDB: d2nsxa1, d2nsxb1, d2nsxc1, d2nsxd1
    automated match to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4

Details for d2nsxa2

PDB Entry: 2nsx (more details), 2.11 Å

PDB Description: structure of acid-beta-glucosidase with pharmacological chaperone provides insight into gaucher disease
PDB Compounds: (A:) glucosylceramidase

SCOPe Domain Sequences for d2nsxa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2nsxa2 c.1.8.3 (A:78-431) Glucosylceramidase, catalytic domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2nsxa2:

Click to download the PDB-style file with coordinates for d2nsxa2.
(The format of our PDB-style files is described here.)

Timeline for d2nsxa2: