SCOPe 2.03: Domain d2nmya_: 2nmy A:

Lineage for d2nmya_ (2nmy A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (8 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (421 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d2nmya_: 2nmy A: [138384]
   automated match to d1s65a_
   complexed with cl, na, roc, so4; mutant

Details for d2nmya_

PDB Entry: 2nmy, 1.1 Å

PDB Description: crystal structure analysis of hiv-1 protease mutant v82a with a inhibitor saquinavir

PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d2nmya_:

Sequence; same for both SEQRES and ATOM records:

>d2nmya_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpaniigrnlltqigatlnf

Timeline for d2nmya_:

• d2nmya_ first appeared in SCOP 1.73, called d2nmya1
  
• d2nmya_ appears in SCOPe 2.02
  
• d2nmya_ appears in SCOPe 2.04
  
• d2nmya_ appears in the current release, SCOPe 2.08