SCOPe 2.08: Domain d2nm1a2: 2nm1 A:1067-1291

Lineage for d2nm1a2 (2nm1 A:1067-1291)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.4: STI-like [50386] (3 families)

5. Family b.42.4.2: Clostridium neurotoxins, C-terminal domain [50399] (3 proteins)
   overall fold is very similar to that of the STI family
   automatically mapped to Pfam PF07951

6. Protein Botulinum neurotoxin [50402] (2 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [50403] (10 PDB entries)

8. Domain d2nm1a2: 2nm1 A:1067-1291 [138370]
   Other proteins in same PDB: d2nm1a1, d2nm1a3
   automated match to d4kbba2

Details for d2nm1a2

PDB Entry: 2nm1, 2.15 Å

PDB Description: Structure of BoNT/B in complex with its protein receptor

PDB Compounds: (A:) botulinum neurotoxin type b

SCOPe Domain Sequences for d2nm1a2:

Sequence, based on SEQRES records:

>d2nm1a2 b.42.4.2 (A:1067-1291) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
sqsnieerykiqsyseylkdfwgnplmynkeyymfnagnknsyiklkkdspvgeiltrsk
ynqnskyinyrdlyigekfiirrksnsqsinddivrkedyiyldffnlnqewrvytykyf
kkeeeklflapisdsdefyntiqikeydeqptyscqllfkkdeestdeigligihrfyes
givfeeykdyfciskwylkevkrkpynlklgcnwqfipkdegwte

Sequence, based on observed residues (ATOM records):

>d2nm1a2 b.42.4.2 (A:1067-1291) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
sqsnieerykiqsyseylkdfwgnplmynkeyymfnagnknsyiklkkdspvgeiltrsk
ynqnskyinyrdlyigekfiirrksddivrkedyiyldffnlnqewrvytykyfkkeeek
lflapisdsdefyntiqikeydeqptyscqllfkkdeestdeigligihrfyesgivfee
ykdyfciskwylkevkrkpynlklgcnwqfipkdegwte

Timeline for d2nm1a2:

• d2nm1a2 first appeared in SCOP 1.73
  
• d2nm1a2 appears in SCOPe 2.07