SCOPe 2.05: Domain d2jbja3: 2jbj A:57-117,A:351-593

Lineage for d2jbja3 (2jbj A:57-117,A:351-593)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
   core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops

4. Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families)
   core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest

5. Family c.56.5.5: FolH catalytic domain-like [53210] (2 proteins)

6. Protein Glutamate carboxypeptidase II FOLH1 [142522] (1 species)
   Folate hydrolase 1, FolH homologue

7. Species Human (Homo sapiens) [TaxId:9606] [142523] (23 PDB entries)
   Uniprot Q04609 57-117,351-593

8. Domain d2jbja3: 2jbj A:57-117,A:351-593 [138252]
   Other proteins in same PDB: d2jbja1, d2jbja2
   automated match to d2c6ca3
   complexed with ca, cl, g88, nag, zn

Details for d2jbja3

PDB Entry: 2jbj, 2.19 Å

PDB Description: membrane-bound glutamate carboxypeptidase ii (gcpii) in complex with 2-pmpa (2-phosphonomethyl-pentanedioic acid)

PDB Compounds: (A:) glutamate carboxypeptidase 2

SCOPe Domain Sequences for d2jbja3:

Sequence, based on SEQRES records:

>d2jbja3 c.56.5.5 (A:57-117,A:351-593) Glutamate carboxypeptidase II FOLH1 {Human (Homo sapiens) [TaxId: 9606]}
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lXevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkke
gwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctp
lmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrl
giasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfela
nsivl

Sequence, based on observed residues (ATOM records):

>d2jbja3 c.56.5.5 (A:57-117,A:351-593) Glutamate carboxypeptidase II FOLH1 {Human (Homo sapiens) [TaxId: 9606]}
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lXevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkke
gwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctp
lmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrl
giasgrarytknfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivl

Timeline for d2jbja3:

• d2jbja3 first appeared in SCOP 1.73
  
• d2jbja3 appears in SCOPe 2.04
  
• d2jbja3 appears in SCOPe 2.06
  
• d2jbja3 appears in the current release, SCOPe 2.08