SCOP 1.75: Domain d2jbja2: 2jbj A:118-350

Lineage for d2jbja2 (2jbj A:118-350)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.8: The "swivelling" beta/beta/alpha domain [52008] (10 superfamilies)
   3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
   this domain is thought to be mobile in most multi-domain proteins known to contain it

4. Superfamily c.8.4: PA domain [52025] (1 family)

5. Family c.8.4.1: PA domain [52026] (2 proteins)

6. Protein Glutamate carboxypeptidase II [141984] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [141985] (14 PDB entries)
   Uniprot Q04609 118-350

8. Domain d2jbja2: 2jbj A:118-350 [138251]
   Other proteins in same PDB: d2jbja1, d2jbja3
   automatically matched to 2C6C A:118-350
   complexed with bma, ca, cl, g88, man, nag, zn

Details for d2jbja2

PDB Entry: 2jbj, 2.19 Å

PDB Description: membrane-bound glutamate carboxypeptidase ii (gcpii) in complex with 2-pmpa (2-phosphonomethyl-pentanedioic acid)

PDB Compounds: (A:) glutamate carboxypeptidase 2

SCOP Domain Sequences for d2jbja2:

Sequence, based on SEQRES records:

>d2jbja2 c.8.4.1 (A:118-350) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
sypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvyv
nyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfap
gvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhpi
gyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvkmhihstn

Sequence, based on observed residues (ATOM records):

>d2jbja2 c.8.4.1 (A:118-350) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
sypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvyv
nyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfap
gvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhpi
gyydaqkllekmggsappdsswrgslkvpynvgpgftfstqkvkmhihstn

Timeline for d2jbja2:

• d2jbja2 first appeared in SCOP 1.73
  
• d2jbja2 appears in SCOPe 2.01
  
• d2jbja2 appears in the current release, SCOPe 2.08