SCOPe 2.03: Domain d2j5lb2: 2j5l B:108-214

Lineage for d2j5lb2 (2j5l B:108-214)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (364 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d2j5lb2: 2j5l B:108-214 [138046]
   Other proteins in same PDB: d2j5la1, d2j5lb1, d2j5lc1, d2j5lc2
   automatically matched to d1dqdl2

Details for d2j5lb2

PDB Entry: 2j5l, 2.9 Å

PDB Description: structure of a plasmodium falciparum apical membrane antigen 1-fab f8. 12.19 complex

PDB Compounds: (B:) fab fragment of monoclonal antibody f8.12.19

SCOPe Domain Sequences for d2j5lb2:

Sequence; same for both SEQRES and ATOM records:

>d2j5lb2 b.1.1.2 (B:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

Timeline for d2j5lb2:

• d2j5lb2 first appeared in SCOP 1.73
  
• d2j5lb2 appears in SCOPe 2.02
  
• d2j5lb2 appears in SCOPe 2.04
  
• d2j5lb2 appears in the current release, SCOPe 2.08