SCOPe 2.07: Domain d2j50b_: 2j50 B:

Lineage for d2j50b_ (2j50 B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d2j50b_: 2j50 B: [138012]
   automated match to d3dfcb_
   complexed with 627, so4

Details for d2j50b_

PDB Entry: 2j50, 3 Å

PDB Description: structure of aurora-2 in complex with pha-739358

PDB Compounds: (B:) serine/threonine-protein kinase 6

SCOPe Domain Sequences for d2j50b_:

Sequence, based on SEQRES records:

>d2j50b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqsh
lrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyc
hskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppemiegrmhd
ekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhn
psqrpmlrevlehpwitanssk

Sequence, based on observed residues (ATOM records):

>d2j50b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqsh
lrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyc
hskrvihrdikpenlllgsagelkiadfgwsvtlcgtldylppemiedekvdlwslgvlc
yeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlrevle
hpwitanssk

Timeline for d2j50b_:

• d2j50b_ first appeared in SCOP 1.73, called d2j50b1
  
• d2j50b_ appears in SCOPe 2.06
  
• d2j50b_ appears in the current release, SCOPe 2.08