SCOPe 2.06: Domain d2j14b_: 2j14 B:

Lineage for d2j14b_ (2j14 B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)

8. Domain d2j14b_: 2j14 B: [137936]
   automated match to d1gwxa_
   complexed with gni

Details for d2j14b_

PDB Entry: 2j14, 2.8 Å

PDB Description: 3,4,5-trisubstituted isoxazoles as novel ppardelta agonists: part2

PDB Compounds: (B:) Peroxisome proliferator-activated receptor delta

SCOPe Domain Sequences for d2j14b_:

Sequence, based on SEQRES records:

>d2j14b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkqlvng
lppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifaml
asivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaa
iilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvteha
qmmqrikktetetslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d2j14b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lkafskhiynaylknfnmtkkkarsiltgkpfvihdietlwqaekgllppykeisvhvfy
rcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlasivnkdgllvan
gsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaiilcgdrpglmnv
prveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvtehaqmmqrikktetet
slhpllqeiykd

Timeline for d2j14b_:

• d2j14b_ first appeared in SCOP 1.73, called d2j14b1
  
• d2j14b_ appears in SCOPe 2.05
  
• d2j14b_ appears in SCOPe 2.07
  
• d2j14b_ appears in the current release, SCOPe 2.08