SCOP 1.73: Domain d2j14b1: 2j14 B:175-439

Lineage for d2j14b1 (2j14 B:175-439)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (32 proteins)

6. Protein Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48527] (8 PDB entries)

8. Domain d2j14b1: 2j14 B:175-439 [137936]
   automatically matched to d1gwxa_
   complexed with gni

Details for d2j14b1

PDB Entry: 2j14, 2.8 Å

PDB Description: 3,4,5-trisubstituted isoxazoles as novel ppardelta agonists: part2

PDB Compounds: (B:) Peroxisome proliferator-activated receptor delta

SCOP Domain Sequences for d2j14b1:

Sequence, based on SEQRES records:

>d2j14b1 a.123.1.1 (B:175-439) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
lkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkqlvng
lppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifaml
asivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaa
iilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvteha
qmmqrikktetetslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d2j14b1 a.123.1.1 (B:175-439) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
lkafskhiynaylknfnmtkkkarsiltgkpfvihdietlwqaekgllppykeisvhvfy
rcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlasivnkdgllvan
gsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaiilcgdrpglmnv
prveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvtehaqmmqrikktetet
slhpllqeiykd

Timeline for d2j14b1:

• d2j14b1 is new in SCOP 1.73
  
• d2j14b1 appears in SCOP 1.75
  
• d2j14b1 appears in the current release, SCOPe 2.08, called d2j14b_