SCOPe 2.07: Domain d2j14a_: 2j14 A:

Lineage for d2j14a_ (2j14 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (212 PDB entries)

8. Domain d2j14a_: 2j14 A: [137935]
   automated match to d1gwxa_
   complexed with gni

Details for d2j14a_

PDB Entry: 2j14, 2.8 Å

PDB Description: 3,4,5-trisubstituted isoxazoles as novel ppardelta agonists: part2

PDB Compounds: (A:) Peroxisome proliferator-activated receptor delta

SCOPe Domain Sequences for d2j14a_:

Sequence, based on SEQRES records:

>d2j14a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkqlvn
glppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifam
lasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfia
aiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvteh
aqmmqrikktetetslhpllqeiykdm

Sequence, based on observed residues (ATOM records):

>d2j14a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlkafskhiynaylknfnmtkkkarsiltshtapfvihdietlwqaeklppykeisvhvf
yrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlasivnkdgllva
ngsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaiilcgdrpglmn
vprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvtehaqmmqrikktete
tslhpllqeiykdm

Timeline for d2j14a_:

• d2j14a_ first appeared in SCOP 1.73, called d2j14a1
  
• d2j14a_ appears in SCOPe 2.06
  
• d2j14a_ appears in the current release, SCOPe 2.08