SCOPe 2.01: Domain d2j0sa2: 2j0s A:244-411

Lineage for d2j0sa2 (2j0s A:244-411)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.19: Tandem AAA-ATPase domain [81268] (24 proteins)
   duplication: tandem repeat of two RecA-like (AAA) domains

6. Protein Probable ATP-dependent RNA helicase DDX48 [142314] (1 species)
   Eukaryotic translation initiation factor 4A isoform 3

7. Species Human (Homo sapiens) [TaxId:9606] [142315] (3 PDB entries)
   Uniprot P38919 22-243! Uniprot P38919 244-411

8. Domain d2j0sa2: 2j0s A:244-411 [137914]
   Other proteins in same PDB: d2j0sc_, d2j0sd_
   automatically matched to 2HYI C:244-411
   protein/DNA complex; protein/RNA complex; complexed with anp, mg

Details for d2j0sa2

PDB Entry: 2j0s, 2.21 Å

PDB Description: the crystal structure of the exon junction complex at 2.2 a resolution

PDB Compounds: (A:) ATP-dependent RNA helicase ddx48

SCOPe Domain Sequences for d2j0sa2:

Sequence; same for both SEQRES and ATOM records:

>d2j0sa2 c.37.1.19 (A:244-411) Probable ATP-dependent RNA helicase DDX48 {Human (Homo sapiens) [TaxId: 9606]}
deltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanft
vssmhgdmpqkeresimkefrsgasrvlistdvwargldvpqvsliinydlpnnrelyih
rigrsgrygrkgvainfvknddirilrdieqyystqidempmnvadli

Timeline for d2j0sa2:

• d2j0sa2 first appeared in SCOP 1.73
  
• d2j0sa2 appears in SCOP 1.75
  
• d2j0sa2 appears in SCOPe 2.02
  
• d2j0sa2 appears in the current release, SCOPe 2.08