SCOPe 2.05: Domain d2j0db1: 2j0d B:30-496

Lineage for d2j0db1 (2j0d B:30-496)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Mammalian cytochrome P450 3a4 [109958] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109959] (6 PDB entries)
   Uniprot P08684

8. Domain d2j0db1: 2j0d B:30-496 [137898]
   complexed with ery, hem

Details for d2j0db1

PDB Entry: 2j0d, 2.75 Å

PDB Description: crystal structure of human p450 3a4 in complex with erythromycin

PDB Compounds: (B:) cytochrome p450 3a4

SCOPe Domain Sequences for d2j0db1:

Sequence, based on SEQRES records:

>d2j0db1 a.104.1.1 (B:30-496) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdpdm
iktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvpii
aqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfventkk
llrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledtqkhrv
dflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimyelathpdvqq
klqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfip
kgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfal
mnmklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesr

Sequence, based on observed residues (ATOM records):

>d2j0db1 a.104.1.1 (B:30-496) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
hglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdpdm
iktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvpii
aqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidsnpqdpfventkklp
fflsitvfpflipilevlnicvfprevtnflrksvkrmkesrflqlmidsqhkalsdlel
vaqsiififagyettssvlsfimyelathpdvqqklqeeidavlpnkapptydtvlqmey
ldmvvnetlrlfpiamrlervckkdveingmfipkgvvvmipsyalhrdpkywtepekfl
perfskknkdnidpyiytpfgsgprncigmrfalmnmklalirvlqnfsfkpcketqipl
klslggllqpekpvvlkvesr

Timeline for d2j0db1:

• d2j0db1 first appeared in SCOP 1.73
  
• d2j0db1 appears in SCOPe 2.04
  
• d2j0db1 appears in SCOPe 2.06
  
• d2j0db1 appears in the current release, SCOPe 2.08